TABLE 5

Sensitivity and specificity of SIMOA toxin assays compared to CDI status using samples that did not get an additional freezing/thawing cyclea

TestSensitivity (% [95% CI]) (n = 47)Specificity (% [95% CI]) (n = 118)
SIMOA toxin A85.1 (71.7–93.8)85.6 (77.9–91.4)
SIMOA toxin B95.7 (85.5–99.5)85.6 (77.9–91.4)
SIMOA toxin A + B95.7 (85.5–99.5)80.5 (72.2–87.2)
C. difficile Tox A/B II72.3 (57.4–84.4)96.6 (91.5–99.1)
  • a Totals of 47 GDH- and CCNA-positive samples and 118 GDH- and/or CCNA-negative samples.