TABLE 5

Detection properties of the different tests by concentration for monospecific P. falciparum uPCR-positive infections (P. falciparum by reference B)

TestMedian HRP2 concn (pg/ml) (IQR)No. of infections detected by category of HRP2 concn (% of uPCR reference)
>2,000 pg/ml100–2,000 pg/ml<100 pg/mlTotal
Lab uRDT1,991 (588–8,377)37 (100)29 (88)9 (19)75 (64)
Lab RDT8,377 (3,910–16,500a)35 (95)2 (6)0 (0)37 (32)
Microscopy4,780 (3,187–14,216)27 (73)6 (18)2 (4)35 (30)
uPCR reference517 (19–3,558)37 (100)33 (100)47 (100)117 (100)
Field uRDT3,910 (882–10,378)34 (94)16 (48)3 (7)53 (47)
Field RDT12,937 (7,811–16,500a)22 (61)0 (0)0 (0)22 (19)
uPCR reference553 (19–3,648)36 (100)33 (100)45 (100)114 (100)
  • a The upper limit of quantification of the reference test was 16,500, which was reached in a total of 17 samples.