TABLE 1

Definitions of reference methods

uPCR resultaQuansys ELISA resultb
PfHRP2 detectedPfHRP2 not detected
P. falciparum DNAP. vivax DNAPlasmodium DNAPlasmodium DNA not detected (negative)P. falciparum DNAP. vivax DNAPlasmodium DNAPlasmodium DNA not detected (negative)
Reference A++++
Reference B++
Reference C++++
  • a Reference A corresponds to Quansys ELISA result only (positive if and only if P. falciparum HRP2 [PfHRP2] antigen present). Reference B corresponds to uPCR result only (positive if and only if P. falciparum DNA present). Reference C combines uPCR and Quansys ELISA (positive if P. falciparum DNA present or if PfHRP2 and Plasmodium DNA [Plasmodium spp. or P. vivax] present).

  • b A sample is considered positive (+) (or negative [−]) according to the reference.