TABLE 4

Sensitivity and specificity of SIMOA toxin assays compared to CDI statusa

TestSensitivity (% [95% CI]) (n = 66)Specificity (% [95% CI]) (n = 174)
SIMOA toxin A84.8 (73.9–92.5)83.9 (77.6–89)
SIMOA toxin B95.5 (87.3–99.1)83.3 (77–88.6)
SIMOA toxin A + B95.5 (87.3–99.1)79.3 (72.5–85.1)
C. difficile Tox A/B II71.2 (58.8–81.7)95.4 (91.1–98)
  • a Totals of 66 GDH- and CCNA-positive samples and 174 GDH- and/or CCNA-negative samples. CI, confidence interval.