Table 1.

B. burgdorferi sensu lato strains used in this study

Species and strainBiological sourceaGeographic locationRAPD typebRAPD clustercRFLP patterndReference(s) or provider
B. burgdorferi sensu stricto (n = 23)
 M20 I. ricinus The Netherlands1IA 29
 M26 I. ricinus The Netherlands1IA 29
 M16 I. ricinus The Netherlands2IA 29
 VS293 I. ricinus Switzerland3IA 30
 M11 I. ricinus The Netherlands4IA 29
 M24 I. ricinus The Netherlands4IA 29
 M12 I. ricinus The Netherlands5IA 29
 VS219 I. ricinus Switzerland6IA 30
 M29 I. ricinus The Netherlands7IA 29
 VS215 I. ricinus Switzerland8IA 30
 M2 I. ricinus The Netherlands9IA 29
 M48 I. ricinus The Netherlands10IA 29
 VS130 I. ricinus Switzerland11IA 30
 VS134 I. ricinus Switzerland11IA 30
 A44SHuman skin (EM)The Netherlands11IA 41
 A91-15DogUnited States12IAS. Rijpkema
 Hum3336 I. pacificus United States13IA 33
 A92-1-2DogUnited States14IA 2
 N40 I. scapularis United States15IA 13,33
 A91-10DogUnited States16IA 2
 HB19Human (blood)United States17IA 6
 A91-9DogUnited States18IAS. Rijpkema
 B31 I. scapularis United States19IAATCC 35210
B. garinii(n = 39)
 NT29 I. persulcatus Japan20IIaC 33
 Ip89 I. persulcatus Russia21IIaC 33
 HT7 I. persulcatus Japan22IIaC 16
 A91SHuman skin (NB)The Netherlands23IIbB 21, 41
 A91CHuman (CSF)The Netherlands23IIbB 41
 A76SHuman skin (CA)The Netherlands23IIbB 21, 41
 A104SHuman skin (NB)The Netherlands23IIbBThis study
 A94SHuman skin (MY)The Netherlands23IIbB 21, 41
 A19SHuman skin (NB)The Netherlands24IIbB 21, 41
 PBiHuman (CSF)Germany25IIbB 47
 A01CHuman (CSF)The Netherlands26IIbB 41
 HT55 I. persulcatus Japan27IIcB 16
 JP5 I. persulcatus China28IIdB 23
 JP12 I. persulcatus China28IIdBZ. F. Zhang
 JP2 I. persulcatus China28IIdB 23
 HT19 I. persulcatus Japan29IIdB 16
 M63 I. ricinus The Netherlands30IIeB 29
 M45 I. ricinus The Netherlands31IIfB 29
 PHeiHuman (CSF)Germany32IIfB 47
 A87SHuman skin (NB)The Netherlands33IIfB 21, 41
 M3 I. ricinus The Netherlands34IIfB 29
 TN I. ricinus Germany35IIfB 47
 M4 I. ricinus The Netherlands36IIfB 29
 M64 I. ricinus The Netherlands36IIfB 29
 M6 I. ricinus The Netherlands37IIfB 29
 M44 I. ricinus The Netherlands38IIfB 29
 A77SHuman skin (NB)The Netherlands39IIfB 21, 41
 A77CHuman (CSF)The Netherlands39IIfB 41
 VSBMHuman (CSF)Switzerland39IIfB 31
 M41 I. ricinus The Netherlands40IIfB 29
 VSBPHuman (CSF)Switzerland41IIfB 30, 31
 20047 I. ricinus France42IIfB 33
 VS102 I. ricinus Switzerland43IIfB 30
 M8 I. ricinus The Netherlands44IIfB 29
 T25 I. ricinus Germany45IIfB 47
 M42 I. ricinus The Netherlands46IIfB 29
 M59 I. ricinus The Netherlands47IIfB 29
 PBrHuman (CSF)Germany48IIfB 47
 VSDAHuman (CSF)Switzerland49IIfB 31
B. afzelii (n = 59)
 A51T I. ricinus The Netherlands50IIID 41
 A48T I. ricinus The Netherlands51IIID 41
 A49T I. ricinus The Netherlands52IIID 41
 A57T I. ricinus The Netherlands53IIID 41
 A50T I. ricinus The Netherlands54IIID 41
 A53T I. ricinus The Netherlands55IIID 41
 A105SHuman skin (EM)The Netherlands56IIIDThis study
 A106SHuman skin (EM)The Netherlands57IIIDThis study
 A40SHuman skin (EM)The Netherlands58IIID 41
 A60T I. ricinus The Netherlands59IIID 41
 A58T I. ricinus The Netherlands60IIID 41
 A59T I. ricinus The Netherlands61IIID 41
 A16SHuman skin (ACA)The Netherlands62IIID 41
 A95SHuman skin (ACA)The Netherlands62IIIDThis study
 A116SHuman skin (EM)The Netherlands63IIIDThis study
 A43SHuman skin (EM)The Netherlands64IIID 41
 A56T I. ricinus The Netherlands65IIID 41
 PKoHuman skin (EM)Germany66IIID 33, 47
 A88SHuman skin (ACA)The Netherlands67IIID 41
 M10 I. ricinus The Netherlands68IIID 29
 A11SHuman skin (ACA)The Netherlands69IIID 41
 A86SHuman skin (ACA)The Netherlands69IIID 41
 A10SHuman skin (EM)The Netherlands70IIID 41
 A13SHuman skin (EM)The Netherlands71IIID 41
 A72T I. ricinus The Netherlands72IIID 41
 A61T I. ricinus The Netherlands72IIID 41
 A71T I. ricinus The Netherlands72IIID 41
 A63T I. ricinus The Netherlands72IIID 41
 A67T I. ricinus The Netherlands73IIID 41
 A108SHuman skin (EM)The Netherlands74IIIDThis study
 A64T I. ricinus The Netherlands75IIID 41
 A68T I. ricinus The Netherlands76IIID 41
 A65T I. ricinus The Netherlands77IIID 41
 A20SHuman skin (EM)The Netherlands78IIID 41
 M55 I. ricinus The Netherlands79IIID 29
 A09SHuman skin (ACA)The Netherlands80IIID 41
 A02SHuman skin (EM)The Netherlands80IIID 41
 A84SHuman skin (EM)The Netherlands81IIID 41
 A03SHuman skin (EM)The Netherlands82IIID 41
 A21SHuman skin (EM)The Netherlands82IIID 41
 A69T I. ricinus The Netherlands83IIID 41
 A70T I. ricinus The Netherlands84IIID 41
 A62T I. ricinus The Netherlands85IIID 41
 A110SHuman skin (ACA)The Netherlands86IIIDThis study
 A114SHuman skin (ACA)The Netherlands86IIIDThis study
 A117SHuman skin (EM)The Netherlands87IIIDThis study
 A111aSHuman skin (ACA)The Netherlands88IIIDThis study
 A111bSHuman skin (ACA)The Netherlands88IIIDThis study
 A33SHuman skin (EM)The Netherlands89IIID 41
 A38SHuman skin (EM)The Netherlands90IIID 41
 VS461 I. ricinus Switzerland91IIID 6, 33
 A73T I. ricinus The Netherlands92IIID 41
 A54T I. ricinus The Netherlands93IIID 41
 A27SHuman skin (EM)The Netherlands94IIID 41
 A52T I. ricinus The Netherlands95IIID 41
 A17SHuman skin (ACA)The Netherlands96IIID 41
 M7Ce I. persulcatus China97IIID 23, 33
 A66T I. ricinus The Netherlands98IIID 41
 A26SHuman skin (ACA)The Netherlands99IIID 41
B. japonica HO14 (n = 1) I. persulcatus Japan100IVE 20, 33
B. valaisiana (n = 12)
 UK I. ricinus England101VF 33, 43
 M53 I. ricinus The Netherlands102VF 29,43
 M57 I. ricinus The Netherlands103VF 29, 43
 AR-2 I. ricinus The Netherlands104VF 33, 43
 M50 I. ricinus The Netherlands105VF 29, 43
 M7 I. ricinus The Netherlands106VF 29, 43
 VS116 I. ricinus Switzerland107VF 30, 43
 M19 I. ricinus The Netherlands107VF 29, 43
 M38 I. ricinus The Netherlands107VF 29, 43
 M47 I. ricinus The Netherlands107VF 29, 43
 M49 I. ricinus The Netherlands108VF 29, 43
 M52 I. ricinus The Netherlands109VF 29, 43
Group DN127 25015 (n = 1) I. scapularis United States110VIK 3,33
Borrelia sp. strain A14S (n = 1)Human skin (EM)The Netherlands111VIIR 41
  • a For human skin isolates, the clinical syndromes of the patient are indicated in parentheses, as follows: NB, neuroborreliosis; CA, carditis; MY, myalgia. CSF, cerebrospinal fluid.

  • b RAPD types were defined at the 95% similarity level.

  • c RAPD clusters were defined at the 45% similarity level between genospecies, and the subclusters of B. garinii were defined at the 60% similarity level.

  • d All RFLP patterns except pattern R for strain A14S were described by Postic et al. (33).

  • e In earlier studies, this strain was designated M7.