Table 1.

Comparison of Cobas Amplicor MTB with culture for detection of M. tuberculosis in sputum specimens from 151 patients with suspected active pulmonary tuberculosis

Specimen type (no. of specimens)Cobas Amplicor MTBa
Sensitivity (%)Specificity (%)Positive predictive value (%)Negative predictive value (%)
All specimens (n = 324)83 (73–91)99 (98–100)97 (89–100)95 (92–98)
Smear positive (n = 55)90 (79–97)NDb 96 (86–99)ND
Smear negative (n = 269)68 (47–85)ND100 (100–100)ND
  • a The 95% confidence intervals are in parentheses.

  • b ND, not determined.