Table 2.

Inter- and intralaboratory variation for determination of the IC50 of ganciclovir for the ganciclovir-sensitive AD169 strain of HCMV

LabGCV IC50 (μM)aCellsh p.i.bMOI (PFU/cell)
11.5HFF962
21.5HFF721
1.5HFF961
3.0MRC-5721
1.5MRC-5721
33.0MRC-5725
43.0HELF481
51.5MRC-57210
1.5MRC-57210
3.0MRC-57210
1.5MRC-57210
  • a Concentration of ganciclovir (GCV) that reduced the number of antigen-positive cells by 50% (IC50).

  • b Hours postinfection.