TABLE 3.

Antifungal activities of amphotericin B against 1,997 invasive isolates of Candida spp., SENTRY, Program, 1997 to 2000

SpeciesNo. of isolates testedCumulative % inhibited at MIC (μg/ml) ofa:
0.060.120.250.512481632
C. albicans1,1140.20.42.738.292.199.5100100100100
C. glabrata3340.60.91.85.741.4b83.397.999.7100100
C. parapsilosis3010.00.00.32.744.1b80.997.099.3100100
C. tropicalis2090.00.00.58.148.8b90.999.5100100100
C. krusei390.00.00.00.010.3c43.682.197.4100100
  • a Amphotericin B MICs were determined by the Etest (overall agreement with the broth microdilution method, 98.7%).

  • b P < 0.001 compared to the results for C. albicans.

  • c P < 0.001 compared to the results for each other species group.