TABLE 5

Sensitivity and specificity of UMT, BinaxNOW Pf, and BinaxNOW Pan tests by parasite density level for febrile, afebrile, and all study participants

Group and testTest performance by parasite densityaP value by density groupb
Specificity (% [CI]) at 0Sensitivity (% [CI])
1–9991,000–4,9995,000+1–9991,000–4,999
Total study population
    UMT89 (87, 91)58 (41, 74)69 (56, 79)86 (81, 90)<0.0010.002
    BinaxNOW Pf75 (72, 77)95 (82, 99)96 (88, 99)100 (98, 100)0.0550.042
    BinaxNOW Pan93 (92, 94)42 (26, 59)70 (58, 80)90 (85, 93)<0.001<0.001
Febrile group
    UMT84 (80, 88)71 (42, 92)76 (59, 89)88 (81, 92)0.1050.107
    BinaxNOW Pf69 (64, 74)93 (66, 100)97 (85, 100)NA0.0830.181
    BinaxNOW Pan86 (83, 90)57 (29, 82)79 (62, 91)NA0.0040.143
Afebrile group
    UMT91 (89, 93)50 (29, 71)61 (43, 77)82 (71, 90)<0.0010.020
    BinaxNOW Pf77 (74, 80)96 (79, 100)94 (81, 99)99 (93, 100)0.0550.253
    BinaxNOW Pan95 (94, 97)33 (16, 55)61 (43, 77)90 (81, 96)<0.0010.001
  • a Parasite density (number of parasites/microliter of blood) was determined by microscopy. NA, not available.

  • b P values are based on a comparison with the results from the 5,000+ density group using Fisher's exact test.