TABLE 6

Urine malaria test (UMT) performance characteristics among study participants infected with Plasmodium falciparum relative to original and PCR-corrected microscopy results

Parameter and groupaUMT performance relative to:P valueb
Original microscopyPCR-corrected microscopy
Sensitivity (% [CI])
    All participants78 (74, 83)77 (72, 81)0.665
    Febrile85 (79, 89)81 (75, 86)0.577
    Afebrile72 (64, 79)72 (66, 79)1.00
Specificity (% [CI])
    All participants90 (89, 91)92 (90, 93)0.368
    Febrile84 (80, 88)85 (81, 89)0.770
    Afebrile92 (90, 93)94 (92, 95)0.091
PPV (% [CI])
    All participants63 (58, 67)70 (65, 74)1.00
    Febrile74 (68, 80)77 (71, 82)1.00
    Afebrile51 (44, 57)63 (56, 69)1.00
NPV (% [CI])
    All participants95 (94, 96)94 (93, 95)0.945
    Febrile90 (87, 93)88 (84, 91)0.891
    Afebrile97 (95, 97)96 (95, 97)0.941
PLR
    All participants0.240 (0.237, 0.243)0.253 (0.249, 0.256)
    Febrile0.201 (0.195, 0.207)0.228 (0.221, 0.236)
    Afebrile0.304 (0.298, 0.311)0.294 (0.287, 0.302)
NLR
    All participants7.87 (7.72, 8.03)9.25 (9.11, 9.40)
    Febrile5.29 (5.04, 5.55)5.49 (5.29, 5.70)
    Afebrile8.70 (8.42, 8.99)11.2 (10.9, 11.5)
  • a PPV, positive predictive value; NPV, negative predictive value; PLR, positive likelihood ratio; NLR, negative likelihood ratio.

  • b P values were estimated by the chi-square statistic for sensitivity and specificity and by the weighted generalized score method for predictive values.