Fraction of drug resistance acquired through person-to-person transmission versus de novo evolution of resistance within individual patients for each druga

DrugNo. of acquisitionsEstimated % de novoEstimated % transmission
First-line drugs
Second-line drugs
Other drugs
  • a Parsimony was used to estimate the number of times genotypic resistance was gained in isolates with AST results. This number was divided by the total number of phenotypically resistant isolates to estimate the fraction of resistance to each drug acquired through de novo evolution, while the remaining fraction was assigned to acquisition from person-to-person transmission.