TABLE 3

Allelic diversity of mmpT5 among clinical isolates of M. intracellulare

mmpT5 positionmmpT5 alleleaNucleotide changeStatusbAmino acid change
1.11.22.13.13.23.34.14.25.15.25.35.46.17.17.27.38.1
56TGT56→GNSIle19→Ser
67GCG67→CNSAla23→Pro
72AGGGGGA72→GSynVal24→Val
74GCG74→CNSArg25→Pro
104TGT104→GNSVal35→Gly
129AGGA129→GSynGlu43→Glu
137TGT137→GNSVal46→Gly
196/197CC196_197→insCcFSGly66→fs
311/312CCC311_312→insCFSPro104→fs
378GAG378→ASynAla126→Ala
429CTTTTC429→TSynVal143→Val
450CTC450→TSynPro150→Pro
471GAAAAAAAAAG471→ASynLeu157→Leu
484GCG484→CNSAla162→Pro
504GG504→ZSynSer168→Ser
522GAAAG522→ASynAla174→Ala
528CTTTTTTTTTTTTTTC528→TSynGly176→Gly
529GAAAAG529→ANSGlu177→Lys
582GAAAG582→ASynAla194→Ala
  • a • identical to allele 1.1 (mmpT5 sequence from M. intracellulare ATCC 13950T).

  • b Syn, synonymous change; NS, nonsynonymous change; FS, frameshift mutation.

  • c insC, insertion of C.