TABLE 6

PROVEAN analysis of nonsynonymous substitutions in SWEH1 to SWEH7 and SWEH14

GenePROVEAN scorea
SWEH1SWEH2SWEH3SWEH4SWEH5SWEH6SWEH7SWEH14
cgd1_1520 fsc *d
cgd1_800
cgd4_2000
cgd4_2850 fs
cgd4_3090
cgd4_60
cgd4_670 (oocyst wall protein 3)
cgd5_3420 fs−3.5
cgd6_200 fs
cgd6_210 (oocyst wall protein 9)−1.75b−1.75−1.75−1.75−1.75−1.75−1.75−2.389
cgd6_3640 fs
cgd6_670 fs
cgd7_1730
cgd7_1800 (oocyst wall protein 2)−2.639 −2.639 −2.639 −4.089
cgd7_4080 fs
cgd7_4310 fs, −4.269
cgd7_5260 −7 fs−3
cgd8_2550
cgd8_280 −3
cgd8_30
cgd8_3240
-cgd8_40 1.769
cgd8_4970 fs
cgd8_50 −1.917
ORF_219046..220926
ORF_526362..530345 −1.768 fs
ORF_897157..898530
ORF_complement (4444..7194)
  • a All column entries denote a deleterious amino acid mutation in that sample.

  • b Numbers denote the PROVEAN score for the most deleterious amino acid mutation in that sample.

  • c fs, presence of a frameshift mutation.

  • d *, presence of a stop codon mutation causing premature termination.