TABLE 2

Results of in vitro antifungal susceptibility test for 30 isolates of Aspergillus section Circumdati

Species (no. of isolates) and parameteraMIC or MEC (μg/ml) forb:
AMBAFGCFGMFGITCPSCVRCTBF
A. ochraceus (3)
    GM16.00.250.040.031.00.312.00.03
    MIC range16.00.12–0.50.03–0.060.031.00.25–0.52.00.03
    Mode16.00.50.030.031.00.252.00.03
A. subramanianii (3)
    GM>16.00.100.030.034.00.794.00.03
    MIC range16.0–>16.00.03–0.250.030.034.00.5–1.04.00.03
    Mode>16.00.250.030.034.01.04.00.03
A. sclerotiorum (6)
    GM4.760.030.040.0311.311.03.360.03
    MIC range4.0–8.00.030.03–0.060.034.0–>16.01.02.0–4.00.03
    Mode4.00.030.030.03>16.01.04.00.03
A. pseudosclerotiorum (8)
    GM5.040.040.030.030.890.251.410.03
    MIC range2.0–>160.03–0.120.03–0.060.030.25–>16.00.12–0.51.0–2.00.03
    Mode4.00.030.030.030.50.252.00.03
A. westerdijkiae (10)
    GM>16.00.140.030.030.460.291.080.03
    MIC range>16.00.03–1.00.03–0.060.03–0.060.12–1.00.12–0.51.0–2.00.03
    Mode>16.00.250.030.030.50.251.00.03
    MIC90>16.00.50.060.060.50.51.00.03
Total (30)
    GM12.820.080.030.031.280.391.740.03
    MIC range2.0–>16.00.03–1.00.03–0.060.03–0.060.12–>16.00.12–1.01.0–4.00.03
    Mode>16.00.030.030.030.50.251.00.03
    MIC90>16.00.50.060.034.01.04.00.03
  • a GM, geometric mean.

  • b AMB, amphotericin B; AFG, anidulafungin; CFG, caspofungin; MFG, micafungin; ITC, itraconazole; PSC, posaconazole; VRC, voriconazole; TBF, terbinafine; MEC, minimum effective concentration for AFG, CFG, and MFG.