Table 2.

Enhancement of test sensitivity using IC

COBAS AMPLICOR test and specimenSensitivity (%)Specificity (%)
Without ICWith ICWithout ICWith IC
C. trachomatis
 Swab94.8 (110/116)97.4 (111/114)99.0 (832/840)99.0 (771/779)
 Urine92.0 (104/113)94.0 (110/117)99.1 (844/852)99.0 (828/836)
N. gonorrhoeae
 Swab93.9 (108/115)94.8 (109/115)98.0 (814/831)97.9 (775/792)
 Urine83.8 (98/117)89.7 (104/116)98.9 (828/837)98.8 (818/828)
M. tuberculosis
 Smear positive98.7 (151/153)98.7 (152/154)90.0 (27/30)89.7 (26/29)
 Smear negative73.6 (92/125)75.6 (93/123)99.0 (4027/4068)99.0 (3906/3947)
HCV72.6 (752/1036)78.2 (802/1025)98.2 (912/929)98.2 (903/920)