Table 5.

Relationship between cagA status andvacA genotype of 158 H. pyloriclinical isolates

vacA alleleNo. of isolates withcagA status:
PositiveNegative
s1aa 1176
s1b102
s2b 319
m1511
mx (m1a)282
m2c 5421
  • a Signal sequence allele s1a correlates with the presence of cagA (P < 0.001 by χ2 test).

  • b Signal sequence allele s2 correlates with absence of cagA (P < 0.001 by χ2 test).

  • c vacA midregion genotype m2 correlates with absence of cagA (P < 0.001 by χ2 test).