Table 1.

Clinical characteristics and laboratory data for 36 patients with early and late skin borreliosisa

Patient no. (gender and age)Tick biteDiagnosis (localization)bResult by:
SerologyCulturePCR
ELISAWestern blottingPETFFT
IgMIgGIgMIgGPCR IPCR IIPCR IPCR II
1 (M, 46)+EM (back of knee)NDNDND++
2 (F, 75)+EM (back of knee)NDND+++++
3 (M, 57)EM (back of knee)+(+)+ND++
4 a (M, 41)c+MEM (forearm)++++NANA++
4 bMEM (hip)+NANA++
5 (M, 56)+EM (elbow)NDND+++++
6 (F, 51)+EM (mamma)NDND+++++
7 (M, 28)EM (back of knee)++++ND+
8 (F, 27)EM (back of knee)+(+)ND+++
9 (M, 51)+EM (thigh)(+)++ND+++
10 (M, 47)+EM (heel)+++(+)+NANA+
11 (F, 57)EM (flank)++++++
12 (F, 47)+EM (foot)+ND+++
13 (M, 54)EM (back of knee)NDND++
14 a (M, 31)c+MEM (upper arm)+++(+)+NANA++
14 bMEM (thigh)+NANA++
15 (M, 41)EM (back knee)++++II
16 (F, 60)ECM (thigh)+(+)++II+
17 (F, 54)ECM (ear)+++ND++
18 (F, 38)ECM (thigh)++(+)(+)ND+
19 (F, 41)ECM (lower leg)+(+)+ND
20 (M, 72)ECM (abdomen)+++ND+
21 (M, 52)ECM (back)(+)+++++
22 (F, 66)+ECM (shoulder)++(+)(+)+NANA++
23 (F, 44)ECM (thigh)+++(+)ND+++
24 (F, 63)+ECM (breast)++ND
25 (M, 38)ECM (abdomen)++(+)(+)+++++
26 (M, 57)+ECM (thigh)NDND+++++
27 (M, 58)ECM (thigh)+++(+)+++++
28 (F, 55)+ECM (abdomen)++ND++++
29 (M, 26)ECM (thigh)+NANA++
30 (M, 64)ECM (back)NDNDND++II
31 (F, 56)+ECMNDNDNANA++
32 (M, 55)ACA (lower leg)+++ND++
33 (F, 75)ACA (hand)(+)++++
34 (M, 52)ACA (hand)(+)+++++++
35 (F, 43)ACA (lower leg)++(+)ND+
36 (M, 76)+ACA (lower leg)++ND
  • a +, positive result; (+), borderline-positive reaction; −, negative result; NA, not available; ND, not done; I, inhibition.

  • b Clinically and histologically confirmed diagnosis.

  • c Two biopsies were done for patient no. 4 and 14.