Table 4.

Nucleotide and amino acid sequence homologies between different vacA m-region genotypes

GenotypeRatio% Similarity of nucleotide (amino acid) sequencesa
Transitions:transversionsbNonsynonymous:synonymouscm1m2am2b
m1 (n = 38)2.470.28495.2 ± 1.1 (91.9 ± 3.1)57.7 ± 0.5 (50.0 ± 2.9)62.9 ± 0.6 (49.9 ± 3.9)
m2a (n = 41)1.360.29496.4 ± 1.2 (94.6 ± 3.1)82.5 ± 0.7 (72.9 ± 6.8)
m2b (n = 3)2.130.28495.7 ± 2.1 (95.3 ± 2.5)
  • a Percentages are based on pairwise comparisons of sequences of the corresponding subtypes and are given as means ± standard deviations.

  • b The values represent the ratio of transitions to transversions, based on pairwise comparisons of all sequences belonging to the same subtype.

  • c The values represent the ratio of nonsynonymous to synonymous substitutions, based on pair-wise comparisons of all sequences belonging to the same subtype.