Table 2.

Susceptibility in antibiotic medium 3 brotha

IsolateNPutative statusbMIC (μg/ml)c
48 h72 h
RangeGeo MModeRangeGeo MMode
CN 129S0.125––0.50.330.5
CN 227S0.0625––10.350.25
CN 327S0.125––20.420.5
CN 428S0.125––0.50.350.25
CN 529S0.0625––
CN 628S0.0625––10.340.25
CN 729S0.0625––10.360.5
CN 938S0.0625––10.380.5
CN 1220S0.125––
CN 844R0.5–20.911.0–8.01.62
CN 1020R1.0––2.01.181
CN 1120R1.0–2.0111.0–2.01.031
  • a Eighty-four C. neoformansisolates were tested by the microdilution methodology in broth in antibiotic medium 3. Isolates CN 1 to CN 12 were tested the indicated number of times (N), while the 72 clinical isolates were tested once each. MICs were determined after 48 and 72 h of incubation.

  • b S, susceptible; R, resistant.

  • c Range, range of MICs; Geo M, geometric mean MIC; Mode, modal MIC.