Table 3.

Comparison of antibiotic resistance patterns of 9,243 pneumococcal isolates with those found in previous periods in Spain

Antibiotic(s)aNo. (%) of strains resistant during:
1979–1984b ( n = 1,381)1985–1989b ( n = 2,577)1990–1996 ( n = 9,243)
P63 (4.6)207 (8.0)1262 (13.7)
T235 (17.0)290 (11.3)388 (4.2)
C13 (0.9)44 (1.7)29 (0.3)
E0 (—)c 7 (0.3)53 (0.6)
PT59 (4.3)84 (3.3)233 (2.5)
PC9 (0.7)27 (1.0)55 (0.6)
PE3 (0.2)1 (—)107 (1.2)
TC342 (24.8)264 (10.2)337 (3.6)
TE2 (0.1)7 (0.3)104 (1.1)
CE0 (—)0 (—)4 (—)
PTC252 (18.2)570 (22.1)1159 (12.5)
PTE5 (0.4)25 (1.0)541 (5.9)
PCE0 (—)6 (0.2)19 (0.2)
TCE21 (1.5)18 (0.7)98 (1.1)
PTCE15 (1.1)199 (7.7)1151 (12.5)
 Total1,019 (73.8)1,749 (67.9)5,540 (59.9)
  • a P, penicillin; T, tetracycline; C, chloramphenicol; and E, erythromycin.

  • b Data include invasive and noninvasive pneumococci.

  • c —, 0% or an insignificant percentage.