Table 4.

Sensitivity, specificity, PPV, and NPV of maternal serology with regard to the detection of a CMV-infected fetus or newborn

TestResultNo. of fetuses or newbornsSensitivityaSpecificitybPPVcNPVd
InfectedUninfected
SeroconversionPositive41210062.525100
Negative020
IgM by ELISAPositive65510026.69.8100
Negative020
IgM WB profilePositive61510072.728.5100
Negative040
  • a (Number of true positives/total number of fetuses or newborns infected) × 100.

  • b (Number of true negatives/total number of fetuses or newborns uninfected) × 100.

  • c (Number of true positives/number of true positives + number of false positives) × 100.

  • d (Number of true negatives/number of false negatives + number of true negatives) × 100.