TABLE 4

MIC ranges and mean MICs of antifungals determined by visual readings

SpeciesMIC range (mean MIC) (μg/ml)
Amphotericin BTerbinafineKetoconazoleFluconazoleItraconazolePosaconazoleVoriconazole
M. sympodialis (24 strains)0.125–4 (1.27)≤0.125 to 16 (1.15)≤0.03 to >4 (1.03)0.25 to >128 (7.09)≤0.015 to >8 (0.37)≤0.015 to >8 (0.36)≤0.003 to >8 (0.38)
M. slooffiae (10 strains)0.5 to >8 (2.85)0.25–4 (1.48)≤0.03 to 0.125 (0.07)0.5–4 (1.95)≤0.015 to 0.06 (0.04)≤0.015 to 0.125 (0.03)≤0.003 to 0.03 (0.02)
M. furfur (5 strains)0.125–4 (1.18)2 to >16 (9.2)≤0.03 to 2 (0.52)4 to >128 (42.4)0.06–1 (0.37)0.03–0.5 (0.24)0.03–2 (0.51)
M. globosa (3 strains)0.25–14>44≤0.015 to >8≤0.015 to 0.03≤0.003 to 0.03
M. restricta (2 strains)≤0.06 to >0.1252 to >16≤0.03 to 0.061–40.03≤0.015 to 0.125≤0.003 to 0.015
M. obtusa (2 strains)1 to >8>16>4>128>8>8>8
M. dermatis (1 strain)a0.50.25≤0.030.50.03≤0.015≤0.003
M. japonica (1 strain)a0.125≤0.125>42≤0.015≤0.0150.015
M. yamatoensis (1 strain)a0.5≤0.1250.0640.060.030.03
M. pachydermatis (1 strain)a≤0.0620.06320.030.030.06
M. caprae (1 strain)a20.25>4>128>8>8>8
M. nana (1 strain)a0.12510.0640.0610.03
M. cuniculi (1 strain)a≤0.061≤0.034≤0.015≤0.0150.03
  • a No range; only the reference strain was tested for these species.