Table 1.

Results of PCR-EIA for detection of S. pneumoniae with CSF specimens from patients with meningitis

CSF specimen sourceNo. of specimens testedNo. of specimens positive by PCR-EIA
Patients with meningitis
 Culture or LA positive for S. pneumoniae87
 Culture or LA positive for H. influenzae40
 Culture positive for other organismsa60
 Culture and LA negative115
Patients without meningitisb91
  • a Other includes Proteus mirabilis (n = 1), pseudomonas (n = 1), coagulase-negative staphylococci (n = 1), alpha-hemolytic streptococci (n = 1), and micrococci (n = 2).

  • b Febrile seizures (n = 2), congenital hydrocephalus (n = 1), neonatal sepsis without meningitis (n = 2), cytophagic panniculitis (n = 1), typhoid fever with encephalopathy (n = 1), pneumococcal pneumonia (n = 1), and pneumococcal scalp abscess (n = 1).