Table 2.

HHV-6 and HHV-7 dual primary infection in British children: antibody responses and detection of DNA from both viruses

Patient no.Age (mo)Day after onset of symptomsSerum or plasma
HHV-6 IgG titeraHHV-6 DNAHHV-7 IgG titeraHHV-7 DNA
Without ureaWith ureaWithout ureaWith urea
13101c 16 NTb <8NT
14d 2,048 32 NT 128 <16 NT
14123c NTNT+<8<8
4e <16<16NTNTNTNT
19 2,048 64 NT 256 <16 NT
  • a Those sera whose antibody titers were reduced eightfold or greater by urea are defined as having low-avidity antibody and the results are highlighted in bold. Those sera whose titers were reduced fourfold or less by urea are defined as having high-avidity antibody.

  • b NT, not tested.

  • c Cerebrospinal fluid contained HHV-6 DNA but not HHV-7 DNA.

  • d Saliva contained HHV-7 DNA but not HHV-6 DNA.

  • e Saliva contained HHV-6 DNA and HHV-7 DNA.