Table 1.

Clinical data for 343 patients with nosocomial candidiasis

Characteristic No. (%) of patients
Sites of isolation
 Blood249 (73)
 Sterile body fluids55 (16)
 Catheter17 (5)
 Tissue10 (3)
Underlying conditions
 Malignant disease96 (28)
 Diabetes24 (7)
 Transplantation20 (6)
 Renal insufficiency20 (6)
 Burn10 (3)
 Trauma6 (2)
 Human immunodeficiency virus infection6 (2)
 Prematurity5 (2)
Predisposing factors
 Antibacterial therapy232 (68)
 Central venous catheter207 (60)
 Stay in intensive care unit155 (45)
 Major surgery139 (41)
 Parenteral nutrition138 (40)
 Steroid therapy67 (20)
 Neutropenia43 (13)
Central venous catheter
 Present207 (60)
 Withdrawn175 (85)
 Cultured (no. positive for yeast)85 (49)
Mortality130 (38)
Antifungal treatments (prediagnosis)
 Fluconazole32 (9)
 Itraconazole4 (1)
 Amphotericin B9 (3)
Antifungal treatments (postdiagnosis)
 Fluconazole210 (61)
 Itraconazole7 (2)
 Amphotericin B152 (44)