Table 5.

Intralaboratory reproducibility of Etest MICs of seven antimicrobial agents against M. abscessus, M. chelonae, and the M. fortuitum group

Drug% Agreementa for isolate
M. abscessusM. chelonaeM. fortuitum group
1801180218071814183118661351135213531359
Amikacin66.7–10066.7–10010066.7–10066.7–10066.7–10010077.8–100100100
Cefoxitin77.8–10088.9–10055.6–10010010010055.6–10077.8–10010066.7–100
Ciprofloxacin10010066.7–10088.9–10044.4–10010066.7–10066.7–100100100
Clarithromycin66.7–10010066.7–10010044.4–10066.7–10066.7–10055.6–10055.6–10055.6–100
Doxycycline10010010055.6–10010010088.9–10088.9–10088.9–10088.9–100
Imipenem66.7–10010088.9–10010010010055.6–10066.7–10044.4–10055.6–100
Trimethoprim-sulfamethoxazole10010010010010010088.9–10088.9–10088.9–10066.7–100
  • a MICs in each 3-dilution range (mode ± log2). Numbers represent the range of percentages of agreement at the four participating laboratories, from the site with the most variability to that with the least variability.