Table 1.

NCCLS V-AST subcommittee-approved MIC QC ranges for veterinary fluoroquinolones compared to those for ciprofloxacina

ATCC QC strainFluoroquinoloneNCCLS QC MIC range (μg/ml)
Staphylococcus aureus ATCC 29213Ciprofloxacin0.12–0.05
Difloxacin0.06–0.5
Enrofloxacin0.03–0.12
Marbofloxacin NDb
Orbifloxacin0.25–2
Premafloxacin0.002–0.008
Sarafloxacin0.06–0.25
Enterococcus faecalisATCC 29212Ciprofloxacin0.25–2
Difloxacin1–4
Enrofloxacin0.12–1
MarbofloxacinND
Orbifloxacin1–8
Premafloxacin0.008–0.03
Sarafloxacin0.5–2
Pseudomonas aeruginosaATCC 27853Ciprofloxacin0.25–1
Difloxacin1–8
Enrofloxacin1–4
MarbofloxacinND
Orbifloxacin2–16
Premafloxacin0.5–2
Sarafloxacin0.12–1
Escherichia coli ATCC 25922Ciprofloxacin0.004–0.016
Difloxacin0.016–0.12
Enrofloxacin0.008–0.03
MarbofloxacinND
Orbifloxacin0.016–0.12
Premafloxacin0.004–0.03
Sarafloxacin0.008–0.03
  • a  Ciprofloxacin QC values are from document M100-S10 (3).

  • b  ND, not determined.