Table 1.

E-test pilot study resultsa

Fungus (no. of isolates tested)Antifungal agentIncubation time (h)E-test MIC range (μg/ml) with:NCCLS MIC range (μg/ml)
RCM-3
A. flavus(5)A240.25–20.5–20.25–1.0
480.5–>80.5–>80.5–>81.0–2
I240.12–1.00.06–0.50.12–0.50.06–0.5
480.25–1.00.06–0.50.12–1.0
A. fumigatus(10)A240.12–0.50.25–0.50.25–1.0
480.25–20.25–1.00.5–80.5–1.0
I240.06–>80.12–>80.12–>80.06–>8
480.12–>80.12–>80.25–>8
F. solani (5)A481.0–>82–>81.0–>81.0–2
I24>8>8>8
48>8>8>81.0–>8
S. apiospermum(5)A482–42–41.0–41.0–8
724–>84–>84–>82–8
I480.5–20.25–1.00.5–20.25–1.0
720.5–20.25–1.00.5–2
R. arrhizus(5)A240.06–0.250.03–0.50.5–20.25–0.5
480.06–>80.03–40.5–40.25–2
I242–>81.0–>82–>80.12–0.25
484–>82–>8>80.25–1.0
  • a Abbreviations: NCCLS MICs, MICs obtained by the NCCLS M38-P microdilution method; E-test MICs, MICs obtained with three solidified media, RPMI with 2% dextrose (R), Casitone agar (C), and antibiotic medium 3 (M-3); A, amphotericin B; I, itraconazole.