TABLE 1

Performance of various GBS detection methods compared to that of the combined gold standarda

PerformanceNo. of samples positive/total (%/95% CI)
SCB cultureCMqPCR assay
Sensitivity58/62 (93.5/0.835–0.979)61/62 (98.4/0.901–0.999)61/62 (98.4/0.901–0.999)
Specificity233/233 (100/0.979–1.0)232/233 (99.6/0.972–0.999)232/233 (99.6/0.972–0.999)
PPV58/58 (100/0.922–1.0)61/62 (98.4/0.901–0.999)61/62 (98.4/0.901–0.999)
NPV233/237 (98.3/0.954–0.994)232/233 (99.6/0.972–0.999)232/233 (99.6/0.972–0.999)
  • a A true positive result is GBS detection by routine and/or CM culture and confirmation by either molecular method.