TABLE 4

Dilution linearity with patient samples for Veris HIV-1 assay

Site and assayaRange evaluated (log10 copies/ml)nRSMER2Slope (95% CI)Intercept (95% CI)Maximum degree of nonlinearity (log10 copies/ml)
Bordeaux2.79–6.84180.1100.9951.05 (1.01–1.09)−0.22 (−0.41 to −0.03)±0.116
Toulouse2.68–6.68200.1370.9931.10 (1.06–1.15)−0.56 (−0.78 to −0.34)±0.171
Sheffield1.54–6.93200.0860.9980.91 (0.89–0.93)0.67 (0.57 to 0.76)b
Milan Niguarda2.62–6.62190.1220.9931.05 (1.01–1.09)−0.19 (−0.39 to 0.02)±0.149
Milan L. Sacco2.73–6.73200.1240.9941.07 (1.03–1.11)−0.39 (−0.59 to −0.18)±0.150
Aachen2.05–6.04160.0460.9991.12 (1.10–1.15)−0.23 (−0.32 to −0.15)±0.025
Berlin1.86–6.86230.1620.9911.02 (0.98–1.06)0.07 (−0.13 to 0.27)±0.213
Barcelona1.91–6.91210.0900.9971.07 (1.04–1.09)−0.39 (−0.52 to −0.25)±0.122
Madrid
    1 ml2.89–6.89200.1370.9931.15 (1.11–1.20)−0.93 (−1.16 to −0.70)±0.111
    0.175 ml2.90–6.90180.1290.9931.16 (1.11–1.21)−1.00 (−1.25 to −0.74)±0.126
  • a All sites except Madrid tested only the 1-ml assay.

  • b —, linear model best, nonlinear models not significantly better at a P level of 0.05.