Table 4.

Outcome of serious infections due to ESBL-producing organisms is inferior when the MIC of antibiotics is 2 to 8 μg/ml

MIC (μg/ml)% (no./total) of patients who:
Experienced failure of cephalosporin therapyDied within 14 days of bacteremia
8100 (6/6)33 (2/6)
467 (2/3)0 (0/3)
233 (1/3)0 (0/3)
≤127 (3/11)18 (2/11)
Totala 54 (15/28)
  • a Includes five patients with whose isolates for which MICs were recorded simply as 0.5 to 4 mg/liter.