Table 6.

Sensitivities and specificities of all assays evaluated

Specimen typeAssay evaluated and resultNo. of specimensSensitivity (%)Specificity (%)
Culture positiveCulture negative
BALLegionella genus LC-PCRa
DFA (genus pool)
L. pneumophilaLC-PCRb
Open lung biopsyLegionella genus LC-PCRa
DFA (genus pool)
WS staining
L. pneumophilaLC-PCRb
L. pneumophilaISHc
  • a Assay target is 5S rDNA and is genus specific only.

  • b Assay target is mip gene and isL. pneumophila species specific.

  • c Assay target is 16S rDNA and is L. pneumophila species specific.