Table 2.

Proposed MIC ranges of various antifungal agents for two quality control strains of Candida spp. when tested by the NCCLS microdilution procedure

Antifungal agentMIC (μg/ml) ranges for microdilution tests with:
C. parapsilosisATCC 22019 at:C. krusei ATCC 6258 at:
24 h48 h24 h48 h
Amphotericin B0.25–2.00.5–4.00.5–2.01.0–4.0
Flucytocine0.06–0.250.12–0.54.0–168.0–32
Fluconazole0.5–4.01.0–4.08.0–6416–128
Voriconazole0.016–0.120.03–0.250.06–0.50.12–1.0
Ketoconazole0.03–0.250.06–0.50.12–1.00.25–1.0
Itraconazole0.12–0.50.12–0.50.12–1.00.25–1.0
Caspofungin (MK0991)0.25–1.00.5–4.00.12–1.00.25–1.0
Ravuconazole (BMS 207147)0.016–0.120.03–0.250.06–0.50.25–1.0
Posaconazole (SCH 56592)0.06–0.250.06–0.250.06–0.50.12–1.0
LY3033661.0–8.01.0–8.00.03–0.250.06–0.5