Table 1.

In vitro activity of voriconazole against 312 clinical isolates of Candida species as determined by the reference broth microdilution methoda

OrganismNo. of isolates testedMIC (μg/ml)b
Range50%90%
C. albicans1740.007–>8.00.0070.03
C. glabrata550.015–8.00.251.0
C. tropicalis310.007–0.250.030.06
C. parapsilosis390.007–0.120.0150.06
C. krusei50.12–0.50.25
C. lusitaniae20.0150.015
C. guilliermondii60.03–0.250.06
All3120.007–>8.00.0150.25
  • a Performed according to NCCLS M27-A (11).

  • b 50% and 90%, MICs at which 50 and 90% of isolates tested, respectively, are inhibited.