IFN-γ levels in PBMC culture supernatants after stimulation with mycobacterial antigens or PHA for Danish outpatient study groups, excluding those not BCG vaccinateda
| Antigen or mitogen | Value type | Level (pg/ml) for group (n): | ||
|---|---|---|---|---|
| CD (56) | UC (64) | Control (63) | ||
| M. aviumPPD | Median | 1,860** | 5,326** | 9,303 |
| Mean ± SEM | 3,837 ± 644 | 6,519 ± 766 | 9,829 ± 761 | |
| Range | 1–19,309 | 1–30,073 | 1–21,327 | |
| M. bovisPPD | Median | 2,243** | 4,176** | 10,734 |
| Mean ± SEM | 4,628 ± 717 | 6,053 ± 771 | 11,685 ± 1,085 | |
| Range | 1–18,245 | 1–29,542 | 1–46,100 | |
| PHA | Median | 10,492** | 9,468** | 15,631 |
| Mean ± SEM | 10,144 ± 740 | 9,635 ± 654 | 14,598 ± 801 | |
| Range | 482–19,425 | 1–19,662 | 1–25,932 | |
↵a Kruskal-Wallis nonparametric ANOVA with Dunn's multiple comparisons test. For IFN-γ release after M. avium PPD stimulation, CD < UC (P < 0.05). For IFN-γ release after M. bovis PPD or PHA stimulation, CD and UC groups were not significantly different. Asterisks denote comparison of CD and UC groups to controls: *, P < 0.01; **, P < 0.001.