Table 2.

PCR results for patients and controls from the United States and Denmarka

Type of resultCDUCControl
USDKUSDKUSDK
Total no. of patients tested304935261830
Total no. of tissues tested1753122121589891
Mean ± SD (range) of tissues tested per patient5.8 ± 2.1 (1–12)6.4 ± 0.8 (4–7)6.1 ± 1.4 (3–9)6.1 ± 0.8 (3–7)5.4 ± 1.6 (2–9)3.0 ± 1.5 (2–7)
No. (range) of positive tissues per patient0–40–30–30–20–10–1
No. (%) of total tissues positive15 (8.6)10 (3.2)21 (9.9)7 (4.4)1 (1.0)2 (2.2)
No. (%) of patients positive9 (30.0)6 (12.2)12 (34.3)4 (15.4)1 (5.6)2 (6.7)
  • a Abbreviations: US, United States; DK, Denmark. Significance: among U.S. groups, CD versus controls, P = 0.07; OR = 7.29 (0.84–63.38); UC versus controls, P = 0.04; OR = 8.87 (1.05–74.99); IBD versus controls, P = 0.03; OR = 8.11 (1.01–65.16); among Denmark groups, no significant differences; among U.S. and Denmark combined groups, CD versus controls, P = 0.06; OR = 3.52 (0.96–12.86); UC versus controls, P = 0.01; OR = 5.33 (1.45–19.59); IBD versus controls, P = 0.02; OR = 4.27 (1.24–14.67). Fisher's exact test, two sided, was used (95% confidence interval). The number tested was less than total number in study for some groups due to failure to acquire samples. The positive rates by group, shown as number positive/total number (percent), are 15/79 (19.0), 16/61 (26.2), and 3/48 (6.3) for CD, UC, and control groups, respectively. The positive rate overall for all IBD patients (CD plus UC) was 31 positive of 140 total (22.1%).