Table 3.

MIC distributions, antimicrobial susceptibilities, and spectra of activity of the different antimicrobial agents tested for the MSSA isolates testeda

Antimicrobial agentNo. of isolates for which (mg/liter) is:MIC50/MIC90% Susceptible
≤0.030.06≤0.120.120.25≤0.50.512>2≤44>48>816>16
Penicillin351283361931301822971,46316/>3215.4
Ampicillin3234447871371501772891,03316/>1616.1
Amoxicillin-clavulanate315181462805326803031571/294.8
Ceftriaxone04131461,604372472279c 2/495.6
Cefepime35204311,2688863412682/496.5
Imipenem1,9741962796111450d 0.12/0.2597.2
Erythromycin217161,011149613103610.5/>877.5
Clindamycin1,6614602062001380.12/0.2593.7
Gentamicin222561,03429347771170.5/194.6
Tetracycline2,02320244≤4/889.7
Doxycycline2,01941946271≤0.5/197.7
Minocycline1,1459112321≤0.25/≤0.2592.3
Ciprofloxacin1916986879318537132030.25/190.6
Gatifloxacine 4711,11046834253383630.06/0.25
Trovafloxacine 1,470504902837824630≤0.03/0.12
Rifampin1,84036613610520.03/0.2597.4
Chloramphenicol03512416371,4741158/896.3
Quinupristin-dalfopristin1851,3726566106000.25/0.595.3
Linezolide,f 211113983886002/2
Teicoplanin103271,574313557100.5/1100
Vancomycin032601,954673000.5/1100
  • a A total of 2,287 MSSA isolates were tested, unless indicated otherwise.

  • b See footnote b of Table 2.

  • c For 9 isolates the MIC was 32 mg/liter, and for 70 isolates the MIC was >32 mg/liter.

  • d MIC, >8 mg/liter.

  • e Investigational drug. No susceptibility breakpoints are available for this drug (10).

  • f Only 1,075 MSSA isolates were tested.