Table 2.

Antimicrobial susceptibilities and PFGE patterns of 17 nonrepetitive K. pneumoniae isolates and their transconjugants

Genotypes of β-lactamases, isolate and transconjugantMIC (μg/ml)aNon-β-lactam antibioticsb to which resistance is shownPFGE pattern
CAZCTXFOXATMIPMMEM
Isolate
 IMP-8 + SHV-12 + TEM1
  99a300>25664>256>2560.50.25CHL, SXT, GEN, TOB, PEF, OFX, CIPA
  99c025>25616>25625610.5CHL, SXT, GEN, TOB, PEF, OFX, CIPA
  99c196>256128>256>25611CHL, SXT, GEN, TOB, PEF, OFX, CIPA
  99c89325632>256>25610.5CHL, SXT, GEN, TOB, PEF, OFX, CIPA
  00m393>256256>256>2560.50.25CHL, SXT, GEN, TOB, PEF, OFX, CIPA
  00m749>25664>256>2560.50.25CHL, SXT, GEN, TOB, PEF, OFX, CIPA
  2907/00>25632>256640.50.25CHL, SXT, GEN, TOB, PEF, OFX, CIPA
  00j910>256128>256>25610.5CHL, SXT, GEN, TOB, PEF, OFX, CIPA
  00m578>25664>256>25641CHL, SXT, GEN, TOB, PEF, OFX, CIPA
  99e843>256128>25612810.5CHL, SXT, GEN, TOBA
  00f195>25664>256640.50.25CHL, SXT, GEN, TOBA
  3599/00>256128>256>25620.5CHL, SXT, GEN, TOB, PEF, OFX, CIPB
  00m869>256128>256>256>25616CHL, SXT, GEN, TOB, PEF, OFX, CIPC
  00d401>256>256>256>256>2568CHL, SXT, GEN, TOBD
 IMP-8 + SHV-11 + TEM1
  99w853>25664>2560.2520.5CHL, SXT, GEN, TOB, AMK, PEF, OFX, CIPE
  3396/00>25632>2560.060.250.25CHL, SXT, TOB, AMK, PEF, OFX, CIPC
  00t801>25632>2560.250.50.5CHL, SXT, TOB, AMK, PEF, OFX, CIPC
Transconjugant
 IMP-8 + SHV-12 + TEM1
  99a30025664>256160.50.25CHL, SXT, GEN, TOB
  99c025>25616>256320.50.25CHL, SXT, GEN, TOB
  99c196256322561610.25CHL, SXT, GEN, TOB
  99c89312816>256320.50.25CHL, SXT, GEN, TOB
  00m3931281612880.250.13CHL, SXT, GEN
  00m74925664256160.250.25CHL, SXT, GEN, TOB
  2907/00>256322561610.25CHL, SXT, GEN, TOB
  00m57825616>256320.50.25CHL, SXT, GEN, TOB
  99e84325664>256160.50.25CHL, SXT, GEN, TOB
  00f1951283212880.50.25CHL, SXT, GEN, TOB
  00d40112832256160.50.25CHL, SXT, GEN, TOB
 IMP-8 + TEM-1
  00m86925632>2560.130.50.25SXT, GEN, TOB
  99w85325664>2560.060.50.5CHL, SXT, GEN, TOB
  • a CAZ, ceftazidime; CTX, cefotaxime; FOX, cefoxitin; ATM, aztreonam; IPM, imipenem; MEM, meropenem.

  • b CHL, chloramphenicol; SXT, trimethoprim-sulfamethoxazole; GEN, gentamicin; TOB, tobramycin; AMK, amikacin; PEF, pefloxacin; OFX, ofloxacin; CIP, ciprofloxacin.