Table 1.

Clinical signs and symptoms and laboratory findings of 16 patients who were positive for M. pneumoniae in any of the four diagnostic tests

PatientPeriod of disease at first sampling (days)Age ESRaLeukocyte count (109/liter)Chest radiograph abnormalitiesCFT titerb in sample:Result of:Diagnosis of M. pneumoniaeinfectionc
IgM IFAPCR on throat specimens at: Culture
12 AMC (n = 92) SSI (n = 16)
1111411011.5+≥128≥128+++++
279767.0+≥128≥128++++
3532511.732≥128+++++
42851512.332≥128++
51416112.3+≥128NAd ++++
67131614≥12864++
769NT6.7+3232+++++
879437.2+≥128≥128+++++
9516247.56464++++
10173116.8168+
117748.53232+
121464311.3+3232+
13182347.9+3216+
144759.1NA88+
1532512.5NA6464+
16333237.8NA3232+
  • a ESR, erythrocyte sedimentation rate; NT, not tested.

  • b From 65 of the 92 included patients a second serum sample was collected 2 to 3 weeks after the first sample. CFT positivity was defined as ≥128 or a fourfold titer rise.

  • c Defined as positive culture and/or positive CFT.

  • d NA, not available.