Table 1.

In vitro susceptibilities of 71 Candida dubliniensis isolates tested against eight antifungal agents

Antifungal agentMIC (μg/ml)% Sa
RangeMIC50MIC90
Fluconazole0.12–640.258.097
Itraconazole0.015–0.50.060.25100
BMS-207147≤0.008–0.25≤0.0080.03100
Sch 565920.015–0.120.030.06100
Voriconazole≤0.008–0.5≤0.0080.03100
MK-09910.03–1.00.250.599
Amphotericin B0.05–0.380.190.25100
5FC≤0.12≤0.12≤0.12100
  • a % S, percentage of strains susceptible to the indicated antifungal agent at the following threshold concentration: fluconazole, <64 μg/ml; itraconazole, BMS-207147, Sch 56592, voriconazole, MK-0991, and amphotericin B, <1.0 μg/ml; or 5FC, <8.0 μg/ml.