Table 2.

ELISA analysis of MEFA-6 for exposed HCV epitopes

Antibody specificityHCV sequence recognized by antibodyMEFA-6 reactivity (S/COa)
Monoclonal antibodies
 Anti-core (c22c)aab10–506.71
 Anti-NS3 (c33c)Linear epitope of c33c6.93
 Anti-NS4 (C100c)aa 1901–19408.56
 Anti-NS4 (5-1-1, type 1)aa 1689–17356.68
 Anti-NS5aa 2278–23136.43
Polyclonal antibodies
 Anti-E1aa 192–3809.72
 Anti-E2aa 404–6623.91
  • a S/CO, signal OD/cutoff OD ratio (cutoff OD = 0.45).

  • b aa, amino acids.