Table 5.

Comparison of MEFA-6 CLIA, Ortho 3.0G ELISA, Abbott 2.0G ELISA, and Chiron RIBA 3.0 for detection of anti-HCV antibodies in a pedigree seroconversion panel

Patient bleed dayS/COaReactivity by Chiron RIBA 3.0
MEFA-6 CLIAC25 CLIAOrtho 3.0G ELISAAbbott 2.0G ELISA
10.280.230.020.2Nonreactive
20.940.260.020.2Nonreactive
7 1.17 b 0.24 1.45 0.4Intermediate
91.270.932.740.8Intermediate
143.54 3.85 4.11 3.9 Intermediate
166.385.254.115.0Intermediate
2010.98.314.115.3 Reactive
  • a S/CO, signal OD/cutoff OD ratio.

  • b Boldface indicates reactive bleed date.