Table 3.

MICs of seven antimicrobial agents for M. abscessus reported by four laboratories

DrugMIC (μg/ml) for isolatea:
180118021807
Mode (range)% AgreementMode (range)% AgreementMode (range)% Agreement
Amikacin16 (8–64)97.232 (16–64)10016 (8–32)100
Cefoxitin32 (8–64)10064 (8–512)97.232 (16–32)100
Ciprofloxacin16 (4–32)91.732 (16–32)10032 (16–32)100
Clarithromycin0.5 (0.03–4)47.2128 (128)1000.25 (0.125–0.5)100
Doxycycline64 (32–64)10064 (16–64)97.264 (64)100
Imipenem8 (4–128)75.016 (8–32)1008 (8–128)86.1
Sulfamethoxazole128 (16–128)97.2128 (128)100128 (128)100
  • a % Agreement, percentage of MICs in each three-dilution range (mode ± log2). High off-scale MICs were converted to the next-highest concentration; low off-scale MICs were left unchanged.