Table 1.

Summary of the characteristics of the various molecular typing methods

MethodologyEase of useEase of interpretationDiscrimination poweraTime to result (days)Intralaboratory reproducibilityInterlaboratory reproducibilitySetup costCost per test
PFGEModerateEasyHigh3GoodGoodModerateModerate
Locus-specific PCR-RFLPEasyEasyModerate1GoodGoodModerateLow
Rep-PCREasyEasyHigh1GoodModerateModerateLow
RAPDEasyEasyHigh1ModeratePoorModerateLow
CFLPModerateModerateModerate2GoodPoorModerateHigh
AFLPModerateEasyHigh2GoodGoodHighModerate
SequencingDifficultModerateHigh2GoodGoodHighHigh
  • a This table is intended to give a relative estimate of discrimination power. For more exacting comparisons, see the references cited in the text.