Table 1.

Precision and reproducibility of Cobas-AM

Sample no.Input HBV DNA (copies/ml)Technician 1Technician 2
Meana(copies/ml)Rangea (copies/ml)CV (%)Within-run CV range (%)Meana(copies/ml)Rangea (copies/ml)CV (%)Within-run CV range (%)
3200258128–495b5025–85317201–756b5719–84
4400544123–1,0304518–97666115–948347–64
58251,064425–2,4005018–791,562885–2,0602812–33
61,6502,0671,100–3,360335–352,6002,060–3,2101510–21
913,30015,52510,400–24,0002310–1621,40017,600–29,000143–22
12106,00097,57575,100–128,000167–19121,33595,000–143,000124–17
  • a Of 20 analyses; quadruplicates of each sample were analyzed repeatedly over 5 days by each technician.

  • b Two nonreactive results of analyses are excluded.