Table 1.

Reciprocal FFN and EIA titers of G9 rotavirus-neutralizing MAbs with G9 rotaviruses

MAbG serotype reactivity in decreasing orderImmunoglobulin classaReciprocal FFN titer with 116EFold change in FFN titer to 116E over other that to G9 virusesbReciprocal direct EIA titer with 116EFold change in EIA titer to 116E over other that to G9 virusesb
F45:69, 5M1 × 103 <−1,000 to −2001 × 103 −300 to −30
F45:59G35 × 103 −16 to −6.03 × 104 −66 to −3.0
WI61:19, 8, 5M5 × 104 <−20 to −4.06 × 104 −18 to 1.0
F45:79, 5M2 × 103 −150 to −502 × 103 −30 to −15
F45:99M1 × 105 −10 to −0.54 × 103 −100 to −75
F45:89M<1 × 102 <−104 to <−1008 × 102 −5,000 to −125
RV-3:23, 9, 5G2bc 3 × 102 −170 to −673 × 103 −660 to 1.5
RV-3:43, 9G14 × 102 −50 to >4.02 × 104 1.0 to 10
F45:19, 4G2a>1 × 106 1.0 to >5.0>1 × 106 ≥−4.0 to >1.0
F45:29, 3, 4A4 × 103 −2.5 to 4.08 × 103 −125 to −4.0
  • a Determined with an EIA kit with subclass- and isotype-specific antisera (Commonwealth Serum Laboratories, Parkville, Victoria, Australia).

  • b The other G9 rotaviruses tested were F45, WI61, and AU32. FFN and EIA titers of MAbs F45:1, F45:2, F45:5, F45:6, F45:7, F45:8, F45:9, and WI61:1 with these rotaviruses were determined previously (34).

  • c Described previously (7).