Table 4.

Agreement of test results based on the tentative breakpoint concentrations (phase II)

DrugStrain categorya (no. of strains)BACTEC 460Middlebrook 7H10
Inhibitory concn (μg/ml)Agreement (%)Inhibitory concn (μg/ml)Agreement (%)
CapreomycinS (14)1.25861094
2.598
R (6)1.251001071
2.5100
CycloserineS (20)75893091
10098
EthionamideS (10)1.2595592
2.5100
R (10)1.2588565
2.572
KanamycinS (11)2.5100598
5.0100
R (9)2.589596
5.089
AmikacinS (12)0.51002.093
1.01004.094
R (8)0.51002.0100
1.01004.0100
ClofazimineS (19)0.125930.598
0.251001.0100
R (1)0.125830.550
0.25831.017
OfloxacinS (19)1.01001.088
2.01002.0100
R (1)1.01001.0100
2.01002.0100
RifabutinS (7)0.5930.5100
1.01001.0100
R (13)0.51000.595
1.0951.091
  • a S, susceptible; R, resistant.