Table 1.

Quantification of HCMV DNA in AF of congenitally HCMV-infected fetuses by quantitative PCR

Group and fetusTime (wks of gestation) of:No. of HCMV DNA GE/ml of AFOutcomea (symptoms)
Maternal infectionPrenatal diagnosis
Group A
 1<10191.25 × 105TOP
 210271.25 × 108Stillbirth
 3<8226.25 × 107TOP
 4<13211.25 × 109TOP
 5<10211.25 × 108Term (yes)
 68231.25 × 108Term (yes)
 711221.25 × 106Term (yes)
Group B
 86216.25 × 106TOP
 96213.75 × 107TOP
 109213.75 × 106Term (none)
 119211.25 × 108Term (none)
 12b11 18/23c3.7 × 101/6.2 × 101cTerm (none)
 13b1118/232.5 × 101/1.6 × 101Term (none)
 1422311.25 × 106Term (none)
 15<12246.25 × 105
292.5 × 106Term (none)
 16<14231.25 × 108Term (none)
 1718218.3 × 101Term (none)
 188183.75 × 106TOP
 197216.25 × 106Term (none)
 208213.75 × 106Term (none)
 2112213.75 × 106Term (none)
  • a TOP, termination of pregnancy; Term, full-term pregnancy.

  • b Fetuses 12 and 13 were twins.

  • c Procedure done twice at 18 (before the slash) and 23 weeks (after the slash) of gestation.