Table 1.

Reactivities of sera from patients at different stages of Lyme disease and from patients with other conditions

Disease and stage (n)No. (%) of serum samples with the indicated reactivitya in a:
VlsE ELISAWhole-cell ELISA
ReactiveEquivocalNonreactiveReactiveEquivocalNonreactive
Lyme disease
 Culture-positive EM (41)26 (63)2 (5)13 (32)25 (61)2 (5)14 (34)
 Early disseminated (12)11 (92)1 (8)0 (0)12 (100)0 (0)0 (0)
 Acute neuroborreliosis (17)17 (100)0 (0)0 (0)17 (100)0 (0)0 (0)
 Lyme arthritis (23)20 (87)1 (4)2 (9)22 (96)0 (0)1 (4)
Syphilis (20)1 (5)1 (5)18 (90)15 (75)1 (5)4 (20)
Non-Lyme arthritis (20)0 (0)0 (0)20 (100)0 (0)0 (0)20 (100)
SLE (20)0 (0)0 (0)20 (100)0 (0)0 (0)20 (100)
None (50)1 (2)2 (4)47 (94)3 (6)0 (0)47 (94)
  • a According to the criteria described in Materials and Methods.