Protease (major and minor) and RT resistance mutations found in 24 matched plasma/DBS from Cameroonian blood banks

Sample identification no.Mutation(s) for resistance to indicated enzymea
ProteaseReverse transcriptase
4K20I, M36IK20I, M36I L210C
5M36I, D60E, L63VM36I, D60E, L63V
8K20R, M36IK20R, M36I
10L33F, M36I, V77IL33F, K20I, M36I, V77I
11M36I, D60E, L63T, I93IFLVM36I, D60E, L63T, I93IFLV
20M36I, L63PM36I, L639 M184ML, Y188YD
24K20I, M36I, L63QK20I, M36I, L63Q
25K20I, M36I, L63IK20I, M36I, L63I
29M36I, D60E, L63V, V77IM36I, D60E, L63V, V77I
32K20I, M36I, L63GISVK20I, M36I, L63GISVV118IV118I
12, 16, 26, 27, 28, 30, 33, 35, 36, 37, 40K20I, M36IK20I, M36I
23, 38, 39K20I, M36I, L63PK20I, M36I, L63P
  • a Mutations in bold were identified in DBS sequences but not in plasma.